Early detection of cancer in high-risk BRCA mutation carriers using liquid biopsies

    Principal Investigator: Victor Velculescu | Affiliation: Johns Hopkins University

    Research Keywords

    Early detection

    Research Questions

    • What are the molecular characteristics of circulation free DNA in BRCA carriers with and without cancer?
    • What is the strategy for screening?

    Specific Aims

    • Aim 1:
    • Aim 2:
    • Aim 3:

    Methods

    1. ctDNA detection
    2. Sequencing
    Last updated on January 5, 2023